The PathCare molecular laboratory has developed an in-house, validated, pan-fungal PCR. Although more than 2 million fungal species are recognized, only 600 are reported to cause human disease and 99% of all human disease are caused by about 30 species. Haematological malignancy with stem cell transplant, neonatal and critical care patients, solid organ transplant patients, cystic fibrosis and HIV positive patients are all at particular risk for fungal infection.